Mechanism of action:

Artvigil (Armodafinil) tablets are a wakefulness-promoting agent for oral administration.Artvigil (Armodafinil) is the R-enantiomer of modafinil which is a mixture of the R- and S-enantiomers. The chemical name for Armodafinil is 2-[(R)-(diphenylmethyl)sulfinyl]acetamide. The molecular formula is C15H15NO2S and the molecular weight is 273.35. Artvigil (Armodafinil) is a white to off-white, crystalline powder that is very slightly soluble in water, sparingly soluble in acetone and soluble in methanol.

Dosage and Administration:

Dosage In Obstructive Sleep Apnea (OSA) And Narcolepsy:

• The recommended dosage for patients with OSA or narcolepsy is 150 mg to 250 mg taken orally once a day as a single dose in the morning. In patients with OSA, doses up to 250 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that these doses confer additional benefit beyond that of the 150 mg/day dose.

Dosage In Shift Work Disorder (SWD):

• The recommended dosage for patients with SWD is 150 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift.

Dosage Modification In Patients With Severe Hepatic Impairment:

• In patients with severe hepatic impairment, the dosage should be reduced.

Use In Geriatric Patients:

• Consideration should be given to the use of lower doses and close monitoring in geriatric patients.

Side effects:

Headache, nausea, dry mouth, nervousness, dizziness, or difficulty sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Store:

Artvigil (Armodafinil) room temperature away from moisture and heat or cold. Do not freeze

Precaution:

Before taking Artvigil (Armodafinil), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

WARNING:

Artvigil is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.