Instgra (Dolutegravir) contains antagonistic to viral property against HIV compose I infection. Instgra is classified as an Integrase inhibitor, which can prepared to limit HIV cell improvement by interfering with Integrase definitive to the dynamic site and blockade of strands trade step happened. The viral DNA mix into have cells get stopped This trade method is responsible for HIV cell increment cycle. This prompts impediment of viral activity
Brand : Instgra
Ingredients : Dolutegravir
Strength : 50mg
Manufactured : emcure
Package : 30 Tablets
In Instgra measurement considers, Creatinine freedom, urine glucose, urine protein esteem ought to be explored. Instgra containing 50mg of Dolutegravir.Dosage recommendation
The standard measurement of Instgra is one tablet of 50mg to be taken as a solitary dosage as orally. Instgra can be taken with or without food but probably taken with food to enhance exposure. In adults: INSTI (Integrase strand transfer inhibitor)For new patients or experienced INSTI new or virologically restrained
The recommended dose of Instgra 50mg should be taken as once a dayFor new or experienced INSTI new by combining with UGT1A or CYP3A inducers
The recommended dosage of Instgra is 50mg should be given as two times a dayFor INSTI already treated with certain INSTI related resistance alternatives
The recommended dosage of Instgra is 50mg should be given as two times a dayIn pediatric
The recommended dosage of Instgra for 30 to less than 40kg patients: 35mg should be taken as a once a day For 40kg or greater patients: The prescribed dosage is 50mg once daily.
For Instgra ; The adverse effects occur in this therapy; Immune reconstitution syndrome Liver toxicity Anaphylactic reactionsThe most common side effects like
Insomnia Anxiety Depression Creatine kinase elevation Increase in lipase Neutrophils elevation
Hypersensitivity reaction: This may occur due to contraindication Lack of virological response during drug interaction: The Resistance of Instgra may occur in some patients during concomitant use with some drugs. Immune reconstitution syndrome: Some immune restructuring ailment is occurred during the initial stage of anti-retro viral therapy Liver damage: Elevation of AST & ALT levels causing liver damage; to avoid this problem monitor the patients with frequent liver function test.