WELCOME TO Million Health Pharmaceuticals

Million-Health-Pharmaceuticals



In adult, Lenvatinib 10mg is indicated for the treatment of metastatic, progressive, radioactive Differentiated Thyroid cancer. Lenvatinib 10mg in combination with everolimus is indicated in patients for the treatment of advance Renal Cell Carcinoma following treatment before anti-angiogenic therapy.

Lenvatinib 10mg is also indicated for the first line treatment in patients suffering with unresectable hepatocellular carcinoma.

Lenvatinib is a tyrosine kinase inhibitor which has shown mainly anti-angiogenic properties, and direct prevention of malignant developed was also observedinside the models.

Lenvatinib which selectively prevents the kinase functions of vascular endothelial growth factor receptors 1(FLT1), 2 (KDR), 3 (FLT4), Although not been studied directly with Lenvatinib, the mechanism of action (MOA) for High blood pressure is hypothesizing to be resolve by the prevention of VEGFR2 in vascular endothelial cells. Same as the, the action for proteinuria is hypothesizing to be interfere with down regulation of VEGFR1 and VEGFR2 in the cell of bowman’s capsules of the glomerulus.





ADME properties Lenvatinib 10mg

Absorption

Time to high plasma concentration is 1-4 hours post dose. Effect with food is low to the extent Lenvatinib of absorption.

Distribution

Bounding of Human plasma proteins is 98% to 99%.

Metabolism

Lenvatinib 10mg is primarily metabolized in CYP3A. Lenvatinib 10mg metabolic pathway is identified as enzymatic and non-enzymatic processes.

Elimination

Eliminated via 64% feces and 25% urine

million-pharma-img

Ingredients : Lenvatinib
Strength : 10mg
Manufactured : Eisai Co. Ltd
Package : 20 Capsules

Dosage and administration of Lenvatinib 10mg

The usual dose of Lenvatinib for the adult patients is 24mg and administer has two 10mg capsules and one 4mg capsule given orally, once daily taken with or without food. The Lenvatinib tablet should continue until disease progression or until unacceptable toxicity occurs. Take Lenvatinib tablet at the same time. Patients with severe renal or hepatic impairment the dose is 14mg administer once daily orally.

OVERDOSE

Lenvatinib is not expected to be dialyzable because of maximum plasma protein binding and if the dose getting of Lenvatinib 120mg orally then causes death due to multiorgan dysfunction occurred in the patients.

Common side effects

Tiredness Peeling of skin on palms and sole of the feet Constipation Loss of appetite Weight loss Joint and muscle pain Insomnia

Serious side effects

Shortness of breath Chest pain Pain in arm, back, neck or jaw Seizures Black, tarry or bloody stools Heavy menstrual bleeding Coughing up blood Yellowing of the skin or eyes

DRUG INTERACTION

Lenvatinib 10mg combination with Carboplatin, paclitaxel has no specific pharmacokinetics impact Interaction with CYP3A, Pglycoprotein (P-gp) inhibitors and inducers has no dose adjustment for Lenvatinib 10mg.



million-pharma-book1

PRECAUTIONS

Blood pressure may increase while treatment with Lenvatinib 10mg . Your doctor will preferably check your blood pressure during your treatment. Inform the doctor if you are allergic to Lenvatinib 10mg , any other regimens, or any of the ingredients in Lenvatinib 10mg capsules.

Other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may to change the doses of your drugs or guide carefully for adverse reaction.

Inform doctor if you have or had seizures, hypertension, a stroke, a heart attack, , especially those due to blood clots, a fistula, a tear in the wall of your GIT, QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death), low levels of Ca,K or Mg in your blood, bleeding problems, or cardiac, renal, or hepatic disease.

Take into the knowledge that Lenvatinib 10mg may reduce the fertility in men and women. It not means that you or your partner cannot become pregnant. Inform doctor before if you are pregnant or plan to become pregnant. After becoming pregnant, you should use birth control while treatment with Lenvatinib 10mg and for at least 2 weeks after your treatment, become pregnant during Lenvatinib therapy, call your doctor immediately. Lenvatinib 10mg may harm the fetus. Inform the doctor if you are breastfeeding or plan to breastfeed. Avoid breastfeed during Lenvatinib 10mg treatment.


Quick Contact





Prescription upload











PRESCRIPTION


Millionpharma.com , a fully licensed and regulated pharmacy medicine, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.

Millionpharma.com will not dispense any prescription medication without a valid prescription from a licensed physician.

If you are ordering prescription medication(s), you hereby confirm that you will send us a scanned copy of your valid prescription(s) via email, fax, Whatsapp, or by post, and this prescription shall then be subject to the scrutiny of and approval by our qualified Pharmacists.

The drug information provided in the Millionpharma.com is for informative purposes only and this Website is not intended to provide diagnosis, treatment or medical advice. We are not liable for any adverse effects or harm to you as a result of your reliance on the information in the Website.

Millionpharma.com requires either the User or Customer or the Caregiver to confirm he/she is completely aware of the indications, side effects, drug interactions, effects of missed dose or overdose of the medicines he/she orders from us. It is imperative to seek professional advice from your physician before purchasing or consuming any medicine from Millionpharma.com

At Millionpharma.com , a Caregiver can order prescription medicines on your behalf.



Disclaimer


This information should not be used to decide whether or not to take this Product or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this Product . It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this product.