Brand : Pirfenex
Ingredients : Pirfenidone
Strength : 200mg
Manufactured : Cipla
Dosage form : film coated tablet
The prescribed dose of tablet Pirfenex in adolescent is 200mg for three times a day (TID), 600mg/day. Based upon the serious of the condition (IPF), dosage may adjust up to 1800mg/day. Dosage of the tablet Pirfenex depending up on symptom. Initially patient starts with 200mg TID, after 2 weeks, dose may gradually increase to 600mg at a time (1800mg/day).Dose adjustment and other consideration for safe use
Patient, during treatment with tablet Pirfenex may affected by gastrointestinal side effects, so patient advice by taking tablet Pirfenex with food. If a symptom sustain means, dose may decrease to 1-2 tablets given for 2-3 times a day with food.Photo sensitive reactions
If rashes endure for 7 days, tablet Pirfenex should be discontinued for 14 days. It is continued by the guidance of health care providers.
Most common side effects caused by Pirfenex include:
• Photosensitivity reactions like rashes
• Decreased appetite
• Stomach pain
• Increased AST and ALT levels
upper respiratory tract infections, UT, Agranulocytosis, Angioedema, Anorexia, weight decreased, loss of appetite, Insomnia, Headache, dizziness, somnolence, dysgeusia, lethargy, Hot flush, Dyspnea, cough, Gastro esophageal reflux, vomiting, constipation, gastritis. ALT, AST increased, serum albumin increased.
Pirfenex tablets should be use with caution; In the conditions like; While patient taking tablet Pirfenex , they may cause to, Increase of liver enzymes Photosensitivity and rash Gastro intestinal disorder Consumption of grapefruit juice: cause inhibit CYP1A2. It should be avoided during the treatment.