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Olysio (Simeprevir) is an antiviral drug used in combination with other medications to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Olysio (Simeprevir) belongs to a class of drugs known as protease inhibitors. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis) or liver cancer.

Brand name:Olysio

Active Ingeridents:Simeprevir

Company Name:Jannsen

Package:28 Capsules

Strength :150mg

Mechanism of action:

Olysio (Simeprevir) functions as a direct-acting antiviral agent because it inhibits hepatitis C viral replication by binding to and inhibiting the protease, hepatitis C virus (HCV) NS3/4A.

Dosage and Administration:

Use Olysio (Simeprevir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Olysio (Simeprevir). Talk to your pharmacist if you have questions about this information.
  • Take Olysio (Simeprevir) by mouth with food.
  • Swallow Olysio (Simeprevir) whole. Do not break, crush, or chew before swallowing.
  • Olysio (Simeprevir) works best if it is taken at the same times each day.
  • Continue to take Olysio (Simeprevir) even if you feel well. Do not miss any doses.
  • Ask your health care provider any questions you may have about how to use Olysio (Simeprevir).


Olysio (Simeprevir) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Diarrhea; dizziness; headache; itching; muscle pain; nausea; tiredness; trouble sleeping.


Store Olysio (Simeprevir) at room temperature up to 86 degrees F (30 degrees C). Keep Olysio (Simeprevir) in the original container. Store away from heat, moisture, and light.Keep Olysio (Simeprevir) out of the reach of children and away from pets.


Before taking Olysio (Simeprevir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.