Brand : Stavir
Ingredients : stavudine
Strength : 30mg
Manufactured : Cipla
Package : 60 Tablets
The prescribed dose of the adult for the treatment of HIV infection
The dosage is mainly based on body weight as follows: The patients weighing < 60kg administer 30mg every 12 hours The patients weighing at least 60kg administered 40mg every 12 hours
Prescribed dose for pediatrics
0.5mg/kg given 12 hours for newborns from birth to 13 days old. 1mg/kg given every 12 hours for pediatric patients at least 14 days old And weighing < 30 kg. Use same adult dose for pediatric patients weighing at least 30kg
The recommended daily dosage exposes no acute toxicity. The chronic dosage complication involves peripheral neuropathy and hepatic toxicity by hemodialysis Stavudine can be removed.
Combination with zidovudine will competitively prohibits the intracellular phosphorylation of Stavudine . Stavir concomitant use with doxorubicin should be taken with caution, it will leads to the phosphorylation of Stavudine is inhibited at relevant concentrations by doxorubicin. While Stavir interaction with ribavirin will reduces phosphorylation of Lamivudine, Stavudine and zidovudine.Contraindication
In patients Stavir capsules is contraindicated with hypersensitivity to Stavudine or to any of the components.