Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zoldonat (Zoledronic acid) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zoldonat (Zoledronic acid) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zoldonat (Zoledronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zoldonat (Zoledronic acid), contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zoldonat (Zoledronic acid).

Store:

Zoldonat (Zoledronic acid) is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zoldonat (Zoledronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.

Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zoldria (Zoledronic acid) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zoldria (Zoledronic acid) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zoldria (Zoledronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zoldria (Zoledronic acid), contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zoldria (Zoledronic acid).

Store:

Zoldria (Zoledronic acid) is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zoldria (Zoledronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.

Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zoldro (Zoledronic acid) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zoldro (Zoledronic acid) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zoldro (Zoledronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zoldro (Zoledronic acid), contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zoldro (Zoledronic acid).

Store:

Zoldro (Zoledronic acid) is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zoldro (Zoledronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.

Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zoldron (Zoledronic acid) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zoldron (Zoledronic acid) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zoldron (Zoledronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zoldron (Zoledronic acid), contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zoldron (Zoledronic acid).

Store:

Zoldron (Zoledronic acid) is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zoldron (Zoledronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.

Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zoledronic is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zoledronic as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zoledronic is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zoledronic, contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zoledronic.

Store:

Zoledronic is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zoledronic, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.

Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zoledronic is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zoledronic as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zoledronic is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zoledronic, contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zoledronic.

Store:

Zoledronic is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zoledronic, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.

Mechanism of action:

The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates such as zoledronate appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; decreased appetite; diarrhea; dizziness; drowsiness; headache; mild cough or sore throat; mild muscle or joint aches; nausea; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Warning:

Zometa (Zoledronic acid) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dosage and Administration:

Use Zometa (Zoledronic acid) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zometa (Zoledronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• If you miss a dose of Zometa (Zoledronic acid), contact your doctor right away.
• Ask your health care provider any questions you may have about how to use Zometa (Zoledronic acid).

Store:

Zometa (Zoledronic acid) is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Precaution:

Before using Zometa (Zoledronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, risedronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, loss of too much body water (dehydration), aspirin-sensitive asthma.