Tinovir-AF 25mg (Tenofovir Alafenamide 25mg) – Overview

Tinovir-AF 25mg is an antiviral medication primarily used for the treatment Chronic Hepatitis B and as a part of combination therapy for HIV-1 infection. As a prodrug of tenofovir, it delivers the active compound more efficiently with fewer side effects compared to earlier formulations.

Medical Uses / Indications

• Chronic hepatitis B virus (HBV) infection in adults and adolescents
• HIV-1 infection (as part of a combination antiretroviral regimen)

How Tinovir-AF 25mg Works (Mechanism of Action)

Tinovir-AF is converted in the body to tenofovir, which inhibits viral reverse transcriptase, an enzyme necessary for viral replication. This prevents the virus from multiplying within infected cells.

Dosage & Administration

• For chronic hepatitis B: 25mg orally once daily, with or without food
• For HIV-1: Dosage and administration depend on the specific combination regimen used
• Always follow the prescribing healthcare provider’s instructions

Possible Side Effects

• Nausea
• Headache
• Fatigue
• Abdominal pain

• Lactic acidosis
• Severe liver problems
• Kidney problems
• Bone loss

Drug Interactions

• May interact with anticonvulsants, certain antivirals, and drugs affecting kidney function
• Always inform your healthcare provider about all medications and supplements you are taking

Precautions

• Use with caution in patients with kidney or liver impairment
• Regular monitoring of kidney and liver function may be needed
• Not recommended during pregnancy or breastfeeding without medical advice

Storage & Handling

• Store at room temperature (20-25°C or 68-77°F)
• Keep in the original container, tightly closed
• Protect from moisture and light

Missed Dose

• Take the missed dose as soon as you remember
• If it is almost time for your next dose, skip the missed dose—do not double up
• Continue with your regular dosing schedule