Alafevir EM Tablet (Tenofovir Alafenamide 25mg + Emtricitabine 200mg) – Overview

Alafevir EM tablet contains Tenofovir Alafenamide 25mg + Emtricitabine 200mg is an antiretroviral medication primarily used for the treatment and prevention of HIV (Human Immunodeficiency Virus) infection. It is often prescribed as part of a comprehensive HIV treatment regimen or as pre-exposure prophylaxis (PrEP) to reduce the risk of acquiring HIV in high-risk populations.

Medical Uses / Indications

• HIV Treatment: This combination is used in adults and pediatric patients to manage and control HIV infection as part of an effective therapy regimen.
• Pre-exposure Prophylaxis (PrEP): For individuals at high risk of HIV exposure, this medication can significantly lower the chances of contracting the virus when taken consistently.

How Alafevir EM tablet Works (Mechanism of Action)

Tenofovir Alafenamide 25mg is a nucleotide reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, a critical component in the life cycle of HIV. Emtricitabine 200mg, also an NRTI, complements this action. Together, they interfere with the replication of the HIV virus, which decreases the viral load in the body and helps maintain a healthier immune system.

Dosage & Administration

• For HIV Treatment: The recommended dosage is one tablet containing Tenofovir Alafenamide 25mg and Emtricitabine 200mg taken once daily, with or without food.
• For PrEP: A similar dosage is recommended, emphasizing adherence to the daily regimen for maximum efficacy.

Possible Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Fatigue
• Headache

Serious side effects may include:

• Kidney problems (e.g., changes in urine output)
• Liver problems (e.g., jaundice)
• Lactic acidosis (a rare but serious condition characterized by a buildup of lactic acid in the blood)

Drug Interactions

Be cautious when using other medications that affect kidney function or are known to increase or decrease the effectiveness of Tenofovir or Emtricitabine. Consult with a healthcare provider for a complete list of potential interactions.

Precautions

• Prior to starting this medication, inform your healthcare provider of any pre-existing renal or liver conditions.
• Regular monitoring of kidney function is essential during treatment.
• Always discuss potential risks and benefits with your healthcare provider.

Storage & Handling

• Store the medication at room temperature, away from moisture and heat. Keep it out of reach of children.
• Do not use the medication past its expiration date.

Missed Dose

If a dose is missed, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for a missed one. Always consult your healthcare provider for specific instructions.