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Abamune L Tablet

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Brand Name: Abamune-L
International Trade Name: Kivexa, Epzicom
Active Substance: Abacavir 600mg + Lamivudine 300mg
Strength: 600mg + 300mg
Category: HIV
Manufacturer: Cipla Ltd
Pack: 30 Tablets in a Bottle
Product Form: Tablet
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Abamune L Tablet (Abacavir 600mg + Lamivudine 300mg) – Overview

Abamune L Tablet contains Abacavir 600mg and Lamivudine 300mg, often prescribed in combination, and are antiviral medications used primarily in the treatment of HIV-1 infection. They belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs) and work by inhibiting the replication of the virus in the body.

 

Medical Uses / Indications

This combination is used for the treatment of HIV-1 infection in adults and pediatric patients. It is essential for managing HIV to reduce the risk of complications, improve quality of life, and lower the possibility of transmission to others.

 

How Abamune L tablet Works (Mechanism of Action)

Abacavir works by inhibiting reverse transcriptase, an enzyme crucial for the HIV replication process. By interfering with viral RNA’s conversion into DNA, it prevents the virus from multiplying. Lamivudine also inhibits reverse transcriptase and has a similar mechanism, enhancing the therapeutic effect of the combination treatment.

 

Dosage & Administration

The usual recommended dosage for adults and children over 12 years of age is one tablet containing 600mg of Abacavir and 300mg of Lamivudine taken once daily. It is essential to follow your healthcare provider’s guidelines regarding dosage and to take the medication at the same time each day for optimal results.

 

Possible Side Effects

Common side effects may include:

  • Nausea
  • Fatigue
  • Headaches

 

Serious side effects may include:

  • Hypersensitivity reactions
  • Lactic acidosis
  • Liver problems

 

Always consult your healthcare provider if you experience severe or concerning symptoms.

 

Drug Interactions

Certain medications may interact with Abacavir and Lamivudine, potentially altering their effects. It is crucial to inform your healthcare provider of all medications, supplements, and herbal products you are taking to avoid interactions.

 

Precautions

Before starting treatment, discuss any pre-existing health conditions with your healthcare provider, particularly liver disease or previous hypersensitivity to Abacavir. Regular monitoring may be required to ensure safe use.

 

Storage & Handling

Store this medication at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and avoid using expired medication.

 

Missed Dose

If you miss a dose of Abacavir 600mg & Lamivudine 300mg, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not take two doses at once.

 

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