Cizumab 400mg Injection (Bevacizumab 400mg) – Overview

Cizumab 400mg Injection contains Bevacizumab 400mg is a monoclonal antibody used as an anti-cancer medication. It works by inhibiting the growth of blood vessels that supply tumors, thereby slowing or stopping tumor growth.

Medical Uses / Indications

Cizumab 400mg Injection (Bevacizumab 400mg) is indicated for the treatment of various cancers, including metastatic colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, and cervical cancer. It may be used alone or in combination with chemotherapy.

How Cizumab 400mg Injection Works (Mechanism of Action)

Cizumab 400mg Injection (Bevacizumab 400mg) targets and binds to vascular endothelial growth factor (VEGF), a protein that stimulates the formation of new blood vessels (angiogenesis). By blocking VEGF, bevacizumab prevents the growth of blood vessels that supply nutrients to tumors, thereby inhibiting their growth.

Dosage & Administration

Cizumab 400mg Injection (Bevacizumab 400mg) is administered as an intravenous infusion by a healthcare professional. The dosage and frequency depend on the type of cancer being treated and the patient’s response. It is often given every 2 or 3 weeks, as determined by the treating physician.

Possible Side Effects

• Common: Fatigue, high blood pressure, nosebleeds, headache, dry skin, and diarrhea.
• Serious: Gastrointestinal perforations, wound healing complications, bleeding, blood clots, severe hypertension, kidney problems (proteinuria), and infusion reactions.
  Seek immediate medical attention if you experience chest pain, shortness of breath, severe headache, or signs of bleeding.

Drug Interactions

Cizumab 400mg Injection (Bevacizumab 400mg) may interact with other medications that affect blood clotting or blood pressure. Inform your doctor of all medications, supplements, and herbal products you are taking.

Precautions

• Not recommended during pregnancy or breastfeeding.
• Inform your doctor if you have a history of bleeding disorders, recent surgery, high blood pressure, or heart disease.
• Monitor for signs of infection, unusual bleeding, or wound healing problems.

Storage & Handling

Cizumab 400mg Injection (Bevacizumab 400mg) should be stored in a refrigerator at 2°C–8°C (36°F–46°F). Do not freeze or shake. Keep out of reach of children and dispose of any unused medication as instructed by your healthcare provider.

Missed Dose

If you miss a scheduled dose, contact your healthcare provider as soon as possible to arrange a new appointment. Do not double up on doses.