Abirabuzz 500mg Tablet (Abiraterone Acetate 500mg Tablet) – Overview

Abirabuzz 500mg Tablet contains Abiraterone acetate, used to treat prostate cancer. It is an androgen biosynthesis inhibitor that lowers the production of testosterone, which can slow the growth of prostate cancer cells.

Medical Uses / Indications

Abiraterone acetate is indicated for the treatment of metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer, usually in combination with prednisone or prednisolone.

How Abirabuzz 500mg tablet Works (Mechanism of Action)

Abiraterone inhibits CYP17, an enzyme required for androgen production. By blocking this enzyme, abiraterone reduces the production of androgens (male hormones) not only in the testes but also in the adrenal glands and the tumor itself, which helps to slow or stop the growth of prostate cancer cells.

Dosage & Administration

• The typical dose is 1000 mg (two 500 mg tablets) taken once daily on an empty stomach (at least 1 hour before or 2 hours after food).
• Abiraterone is usually given with prednisone or prednisolone to reduce the risk of side effects.
• Tablets should be swallowed whole with water and not crushed or chewed.
• Follow your doctor’s instructions carefully.

Possible Side Effects

Common side effects:

• High blood pressure
• Low potassium levels
• Fluid retention (swelling in legs or feet)
• Liver function changes
• Joint pain
• Hot flushes

Serious side effects:

• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
• Liver problems (yellowing of the skin or eyes, dark urine, severe stomach pain)
• Heart problems (irregular heartbeat, chest pain, shortness of breath)

Contact your healthcare provider if you experience any serious or persistent side effects.

 Drug Interactions

• Abiraterone may interact with medications such as rifampicin, phenytoin, carbamazepine, ketoconazole, and certain heart medications.
• Inform your doctor about all medicines, supplements, and herbal products you are taking.

Precautions

• Not for use in women or children.
• Use effective contraception if your partner is of childbearing potential.
• Inform your doctor about any history of heart, liver, or adrenal problems.
• Regular monitoring of blood pressure, liver function, and potassium levels is required.

Storage & Handling

• Store at room temperature (20°C to 25°C/68°F to 77°F), away from moisture and heat.
• Keep in the original packaging and out of reach of children.

Missed Dose

• If you miss a dose, take your usual dose at the next scheduled time.
• Do NOT take extra tablets to make up for a missed dose.
• Inform your doctor if you miss doses frequently.