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Afanat 40mg Tablet

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Brand Name: Afanat 40mg Tablet
International Trade Name: Gilotrif
Active Substance: Afatinib
Strength: 40mg
Category: Anti-Cancer
Manufacturer: Natco Pharma Ltd
Pack: 28 Tablets in a Bottle
Product Form: Tablet
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Afanat 40mg Tablet (Afatinib 40mg Tablet) – Overview

 

Afanat 40mg tablets contains Afatinib 40mg is a prescription medication used in the treatment of certain types of non-small cell lung cancer (NSCLC). It belongs to a class of medicines called tyrosine kinase inhibitors.

 

 Medical Uses / Indications

Afanat 40mg tablet (Afatinib 40mg) is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have specific mutations in the epidermal growth factor receptor (EGFR) gene.

 

How Afanat 40mg tablet Works (Mechanism of Action)

Afanat 40mg tablet (Afatinib 40mg) works by blocking the activity of EGFR, a protein involved in the growth and spread of cancer cells. By inhibiting this protein, Afatinib helps to slow down or stop the progression of cancer.

 

Dosage & Administration

  • The usual recommended dose is 40 mg taken orally once daily.
  • Take at the same time each day, with or without food.
  • Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
  • Your doctor may adjust your dose based on your response and side effects.

 

Possible Side Effects

Common side effects may include:

  • Diarrhea
  • Skin rash or acne
  • Mouth sores
  • Dry skin
  • Loss of appetite

Serious side effects may include:

  • Severe diarrhea or dehydration
  • Liver problems (yellowing of the skin/eyes, dark urine)
  • Severe skin reactions (blistering, peeling)
  • Difficulty breathing or persistent cough
  • Eye problems (redness, pain, vision changes)

Contact your doctor immediately if you experience serious side effects.

 

Drug Interactions

  • Afatinib may interact with other medications, including certain antacids, antibiotics, or herbal supplements.
  • Tell your healthcare provider about all medicines and supplements you are taking.

 Precautions

  • Inform your doctor if you have a history of liver, kidney, or lung problems.
  • Use effective contraception during treatment and for at least 2 weeks after the last dose.
  • Not recommended during pregnancy or breastfeeding.

Storage & Handling

  • Store at room temperature (20–25°C or 68–77°F).
  • Keep the tablets in the original container, tightly closed.
  • Keep out of reach of children.

Missed Dose

  • If you miss a dose, take it as soon as you remember unless it is less than 12 hours until your next dose.
  • Do not take two doses at the same time to make up for a missed dose.

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