Cimivir-L 400mg/90mg Tablet (Sofosbuvir 400mg & Ledipasvir 90mg) – Overview

Cimivir-L tablet is a prescription medication primarily used in the management of chronic hepatitis C virus (HCV) infection. It is a combination of two antiviral agents, Ledipasvir 90mg and Sofosbuvir 400mg, which work together to interfere with the viral replication process.

Medical Uses / Indications

Cimivir-L tablet is indicated for the treatment of chronic hepatitis C infection in adults. It may be used as part of a complete treatment regimen for those with specific genotypes of the virus, helping to achieve sustained virologic response (SVR).

How Cimivir-L tablet Works (Mechanism of Action)

Cimivir-L tablet contains Ledipasvir 90mg and Sofosbuvir 400mg. Ledipasvir acts as an inhibitor of the HCV NS5A protein, which is essential for viral replication and assembly. Sofosbuvir, on the other hand, is a nucleotide analog that inhibits the HCV NS5B polymerase, preventing viral RNA synthesis. Together, they effectively halt the virus’s ability to replicate and spread.

Dosage & Administration

The recommended dosage of Cimivir-L tablet is one tablet taken orally once daily, with or without food. Treatment duration may vary based on the specific HCV genotype and patient history. It is crucial to adhere to the prescribed regimen to maximize the chances of a successful treatment outcome.

Possible Side Effects

Common side effects may include:

• Fatigue
• Headache
• Nausea
• Insomnia Serious

side effects can include:

• Liver problems (e.g., jaundice, dark urine)
• Severe allergic reactions (e.g., rash, itching, swelling)
• Heart rhythm issues

Patients should contact their healthcare provider immediately if they experience any severe side effects.

Drug Interactions

Cimivir-L tablet may interact with certain medications, including:

• Anticonvulsants (e.g., carbamazepine, phenytoin)
• HIV medications (e.g., ritonavir)
• Some antifungals (e.g., ketoconazole)

It’s essential to inform the healthcare provider about all medications and supplements being taken to avoid potential interactions. 

Precautions

Before starting Cimivir-L tablet, patients should disclose their complete medical history, especially any liver problems, prior antiviral treatment, or allergies. It is also not recommended during pregnancy unless specifically advised by a healthcare professional.

Storage & Handling

Cimivir-L tablets should be stored at room temperature, away from moisture and direct sunlight. Keep out of reach of children. If the medication is past its expiration date, dispose of it properly and consult a pharmacist.

Missed Dose

If a dose of Cimivir-L tablet is missed, take it as soon as remembered. However, if it’s nearly time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take two doses at the same time to make up for the missed dose. Always consult a healthcare professional for more information and guidance regarding Ledifos treatment.