Entelet 0.5mg (Entecavir 0.5mg) – Overview

Entelet 0.5mg is an antiviral medication used primarily to treat chronic hepatitis B virus (HBV) infection. It helps to reduce the amount of HBV in the body, improving liver function and decreasing the risk of liver damage.

Medical Uses / Indications

Entelet 0.5mg is indicated for the treatment of chronic hepatitis B in adults and pediatric patients aged 2 years and older. It is effective for patients with evidence of active viral replication and either hepatitis B e antigen (HBeAg) positivity or increased liver enzyme levels.

How Entelet 0.5mg Works (Mechanism of Action)

Entelet works by inhibiting the reverse transcriptase enzyme related to the hepatitis B virus, which is crucial for viral replication. This action helps to decrease viral load in the bloodstream and within the liver, thereby assisting in the treatment of hepatitis B.

Dosage & Administration

The typical dosage of Entelet for adults is 0.5 mg once daily for those who are new to treatment, and it may be increased to 1 mg daily for patients who have developed resistance to other antiviral medications. It is essential to take Entelet on an empty stomach, at least 2 hours before or after a meal, to ensure proper absorption.

Possible Side Effects

Common side effects of Entelet 0.5mg may include:

• Fatigue
• Headache
• Dizziness
• Nausea

Serious side effects can include: 

• Lactic acidosis (a serious metabolic condition)
• Liver problems (indicated by jaundice, dark urine, or abdominal discomfort)
• Risk of hepatitis flare-up after discontinuation of therapy

Patients should contact their healthcare provider immediately if they experience any concerning symptoms.

Drug Interactions

Entelet 0.5mg may interact with other medications, including immunosuppressants and other antiviral drugs. It is crucial to inform your healthcare provider of all medications you are currently taking to avoid potential interactions.

Precautions

Before starting Entelet 0.5mg, patients should discuss their complete medical history with their healthcare provider, especially concerning liver disease and any prior exposure to antiviral treatments. Regular liver function tests are recommended during treatment.

Storage & Handling

Entelet 0.5mg should be stored at room temperature, away from light and moisture. Keep it out of reach of children. Do not use past the expiration date listed on the packaging.

Missed Dose

If a dose of Entelet is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double up on doses to make up for the missed one.

For further inquiries or personal health advice regarding Entelet 0.5mg, please consult your healthcare provider.