Zidine-300 Tablet
Brand Name: Zidine-300 Tablet
International Trade Name: Retrovir
Active Substance: Zidovudine 300mg
Strength: 300mg
Category: HIV
Manufacturer: Emcure Pharmaceuticals Ltd
Pack: 60 Tablets in a Bottle
Product Form: Tablet
- Estimated Delivery : Up to 4 business days
- Free Shipping & Returns : On all orders over $200
Zidine 300mg Tablet (Zidovudine 300mg) – Overview
Zidine 300mg tablet contains Zidovudine 300mg is an antiretroviral medication used to treat human immunodeficiency virus (HIV) infection. It belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).
Medical Uses / Indications
- Treatment of HIV-1 infection in adults and children
- Prevention of maternal-fetal HIV transmission during childbirth (in combination with other antiretrovirals)
How Zidine 300mg Tablet Works (Mechanism of Action)
Zidovudine inhibits the activity of reverse transcriptase, an enzyme crucial for the replication of HIV. By blocking this enzyme, Zidovudine prevents the virus from multiplying and reduces the amount of HIV in the body.
Dosage & Administration
- Adults: Commonly 300mg orally every 12 hours (twice daily), or as prescribed by a healthcare provider
- Children: Dosage is based on body weight or body surface area; follow healthcare provider instructions
- Can be taken with or without food
Possible Side Effects
Common:
- Headache
- Nausea
- Vomiting
- Loss of appetite
- Fatigue
Serious:
- Anemia or neutropenia (low blood counts)
- Lactic acidosis
- Liver problems
- Muscle pain or weakness
- Severe allergic reactions
Drug Interactions
- Other antiretroviral drugs (dose adjustments may be needed)
- Drugs causing bone marrow suppression (e.g., ganciclovir, interferon)
- Ribavirin
- Some chemotherapy agents
- Always inform your healthcare provider of all medications you are taking
Precautions
- Monitor blood counts regularly during treatment
- Use with caution in patients with liver or kidney problems
- Not recommended for breastfeeding mothers with HIV
- Inform your doctor of any history of anemia or muscle disorders
Storage & Handling
- Store at room temperature (20–25°C or 68–77°F)
- Protect from moisture and light
- Keep out of reach of children
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
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