Isentress 400mg Tablet (Raltegravir 400mg) – Overview

Isentress 400mg contains Raltegravir 400mg, is an antiretroviral medication used primarily for the treatment of HIV (Human Immunodeficiency Virus). It belongs to a class of drugs known as integrase strand transfer inhibitors (INSTIs), which help to prevent the virus from multiplying in the body.

Medical Uses / Indications

Raltegravir is indicated for the treatment of HIV-1 infection in both adults and children. It is often prescribed as part of a combination therapy regimen along with other antiretroviral agents.

How Isentress tablet Works (Mechanism of Action)

Raltegravir works by inhibiting the integrase enzyme, which is crucial for HIV’s replication process. By blocking this enzyme, Raltegravir prevents the integration of viral DNA into the host cell’s genome, thereby stopping the virus from replicating and spreading within the body.

Dosage & Administration

The typical recommended dosage for adults and pediatric patients over the age of 12 is 400mg taken orally, twice daily with or without food. It’s essential to follow your healthcare provider’s instructions regarding dosage and to take Raltegravir consistently for optimal effectiveness.

Possible Side Effects

Common and serious side effects may include:

Common side effects:

• Insomnia
• Headache
• gastrointestinal disturbances (nausea, diarrhea)

Serious side effects:

• Allergic reactions (rash, itching)
• liver problems (yellowing of the skin or eyes, dark urine)
• muscle pain or weakness.

Patients should report any severe or concerning side effects to their healthcare provider immediately.

Drug Interactions

Raltegravir may interact with certain medications, which can affect its efficacy or increase the risk of side effects. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking.

Precautions

Use Raltegravir with caution in patients with a history of liver disease or those who are pregnant or breastfeeding. Regular monitoring of liver function and overall health is advised during treatment.

Storage & Handling

Store Raltegravir at room temperature away from moisture and direct sunlight. Keep all medications out of the reach of children and pets. Dispose of any unused medication as directed by a pharmacist or local waste disposal regulations.

Missed Dose

If a dose of Raltegravir is missed, take it as soon as remembered unless it is almost time for the next scheduled dose. In that case, skip the missed dose and resume the normal dosing schedule. Never double the dose to catch up.